春水堂视频

Ph.D.: University of Buenos Aires, 1995 Pharm. D. University of Buenos Aires, 1989 Postdoctoral Fellow: School of Medicine Stanford University, 1995-2001 Awards: New Scholar in Global Infectious Disease. The Ellison Medical Foundation (2004)Junior Faculty Development Award. University of Colorado at Boulder (2003)Scientist Development Award. American Heart Association (2003-present)

By locking the seam of BamA, I aim to indentify the mechanism by which the BAM complex is able to insert nascent outer membrane proteins (OMPs). Using both in vivo and in vitro assays, I can measure the activity of BamA and how locking the barrel effects that activity. The aim of this project is to identify if BamA uses lateral gate opening to directly pass nascent OMPs into the...

My current project focuses on investigating protein unfolding and refolding dynamics using atomic force microscopy (AFM). We have developed a novel method for protein attachment to both AFM surfaces and tips, greatly increasing data acquisition and accuracy. We hope to use this new method to elucidate the evolutionary constraints on proteins that use the type III secretion system of gram negative bacteria. My newest project aims to measure the unfolding...